Hopefully this library will officially be ported to .NET Standard soon. jcaillon already did it, but there is a problem with the HttpResponse class, so maybe you can fix that early:
The FileHandler does not work in .NET Core, it returns the file content before the HTTP 1.1 ... status line and headers.
It can be fixed by inserting writer.Flush(); before await ContentStream.CopyToAsync(writer.BaseStream).ConfigureAwait(false); in HttpResponse.WriteBody.